Topic of the month

Coenzyme Q10 and migraines

Did you know?

Migraines are not normal headaches. The pain, which is usually on one side of the head, can be described as “throbbing” and increases with physical activity. Migraine attacks can also be accompanied by nausea, vomiting and extreme sensitivity to light and noise. The World Health Organisation classifies migraines among the top 20 illnesses with a negative impact on sufferers’ quality of life.

What triggers migraines?

In a study, researchers at the University of Maine in the United States identified 22 factors that can trigger a migraine1. Alcohol, stress and pollution are some of the commonest triggers. They can lead to overproduction of free radicals in the body. This state is called oxidative stress.

Natural protective mechanisms exist to counter this oxidative disorder. Free radicals can be neutralised by a family of molecules with the opposite properties: antioxidants. Vitamin E, for example, has antioxidant properties and helps protect cells against oxidative stress2. There are also other molecules with similar physicochemical properties; one of these is coenzyme Q10, which is well documented by the scientific community (under the name ubiquinol) and well known to the general public, in particular in cosmetics, for its antioxidant and anti-ageing benefits, but what is not known is...

The impact of coenzyme Q10 on migraines!

A double-blind randomised placebo-controlled clinical trial3, carried out by researchers at University Hospital Zurich and at the University of Liège, showed that coenzyme Q10 can reduce the frequency of migraines.

The trial was conducted over three months on 42 participants suffering from repeated migraines. The daily dose of coenzyme Q10 or of placebo was a 100 mg capsule, three times a day. The clinical results showed that coenzyme Q10 reduced the frequency of migraines in one-third of participants compared with only 14% in the placebo group. The members of the Q10 group saw an improvement from the first month and even more significant benefits after taking it for three months.

Coenzyme Q10 is also recommended for other uses, notably for chronic fatigue but also for patients with heart disease and for sports people4. 

AQtif 100, the winning combination of coenzyme Q10 and vitamin E

The food supplement AQtif 100 comes in the form of capsules each containing 100 mg of coenzyme Q10 and 12 mg of natural vitamin E (100% RI), which helps protect cells against oxidative stress. Find out more about AQtif 100.


1 Borkum JM - Department of Psychology, University of Maine, Orono, ME, USA. - Migraine Triggers and Oxidative Stress: A Narrative Review and Synthesis (2015)

2Vitamin E helps protect cells against oxidative stress.

3Sandor PS - Efficacy of CoQ10 in migraine prophylaxis - a randomized controlled trial (2005) - Headache and Pain Unit, Neurology Department, University Hospital Zurich.

4 Coenzyme Q10 at (in French[EB1] ): https://www.passeportsante.net/fr/Solutions/PlantesSupplements/Fiche.aspx?doc=coenzyme_q10_ps

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