BENZADERMINE gel, composed of erythromycin (3%) and benzoyl peroxide (5%), is a medicinal product for local treatment of acne vulgaris.
Erythromycin is a macrolide antibiotic that eliminates propionibacteria in the sebum by bacteriostatic action.
This results in a reduction of the quantity of free fatty acids on the skin's surface as well as a decrease in chemotactic factors which favour inflammation.
Benzoyl peroxide has keratolitic properties and has an antibacterial activity against propionibacterium acnes due to its oxidising power.
Start the treatment with one application per day, then increase to 2 applications per day, morning and evening.
Bright sunlight and U.V. lamps are to be avoided during treatment.
The gel must be used within 2 months of its preparation by the pharmacist.
A multicenter, double-blind, controlled study of the combination of erythromycin/benzoyl peroxide, erythromycin alone and benzoyl peroxide alone in the treatment of acne vulgaris?A.R. Shalita and al., Cutis (1992) 49 (6A) ;1-4
A double-blind study of effectiveness of 3% erythromycin and 5% benzoyl peroxide combination in the treatment of acne vulgaris?D.K. Chalker, MD, and al., J. Am. Acad. Dermatol. 1983 ; 9 : 933-936
Comparison of the combination of erythromycin/benzoyl peroxide topical gel to clindamycin phosphate solution in treatment of acne vulgaris?O.H. Mills, R.S.Berger, Cutis 1992 ; 49 (6A) : 5-7
No result was found for your search